University of CambridgeCambridge University HospitalsNational Institute for Health Research

OPACE: Optimising Azithromycin prevention treatment in COPD to reduce Exacerbations

Welcome to the OPACE trial: Optimising Azithromycin prevention treatment in COPD to reduce Exacerbations.

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Welcome to the OPACE trial. This is a clinical trial to improve treatments for people with chronic obstructive pulmonary disease (COPD). Participants are monitored throughout the trial and receive trial follow-up care, which can be done via telephone or video consultation if preferred, allowing them to participate from home.

The OPACE trial is funded by the National Institute of Health and Care Research (NIHR).

If you decide to take part in this trial, you will be playing an important part in understanding more about how to treat and manage COPD in the future. Without you, and others volunteering to take part in clinical trials like this, treatment for COPD would not be able to progress. Thank you.

If you have COPD and would like to participate in the trial, please head to our Participant Information page [LINK].

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For Potential Participants

We encourage you to consider participating in this trial if:

  • You have chronic obstructive pulmonary disease (also known as COPD) and
  • You have been on the antibiotic Azithromycin or a similar type of antibiotic for at least 3 months.

We are looking for volunteers to join this trial from across the UK.

Please click here for more information.

Further information can also be found in the trial video below.

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For Healthcare Professionals

We encourage participation in this trial from primary and secondary care sites across the UK, especially from areas with high chronic obstructive pulmonary disease (COPD) prevalence.

If you work in GP practices or secondary care sites (including participant identification centres – PICs), please click here to find out more about the trial and how to become a trial site.

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Trial News
Summer 2024 Newsletter

  Welcome to the first OPACE newsletter! Many thanks to you all for your hard work and support in this trial.   SITES UPDATE    We currently have 12 research sites active for OPACE, which include: Primary Care Sites Secondary Care Sites ·  Heath Lane Surgery ·  Vauxhall Primary Health Care ·  Knutsford Medical Partnership ·  […]

Read More… from Summer 2024 Newsletter
All approvals received for OPACE trial!

  As of 26th Sep 2023, we are pleased to confirm final approvals have been received from the Medicines and Healthcare products Regulatory Agency (MHRA), the Research Ethics Committee (REC), and Health Research Authority (HRA) for the OPACE trial to proceed. What happens next? Following approvals, we can start initiating and activating sites to begin […]

Read More… from All approvals received for OPACE trial!

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